Oxidative stress is critical in different conditions, including hypertension, heart failure, hypoxia, ischemia-reperfusion injury, atherosclerosis, and hypertrophy. The condition plays a major role in the pathogenesis of many ailments like cancer, diabetes, and cardiovascular and neurodegenerative diseases, alongside ageing. Researchers at RGCB- National Institute under the Ministry of Science & Technology (Department of Biotechnology) have found the relation between mRNA processing to oxidative stress response. Dr Laishram said controlling oxidative stress is important for keeping cells healthy and preventing human diseases. The research is published in the prestigious Redox Biology journal. The study shows a new cleavage imprecision-mediated anti-oxidant response that is distinct from the other pathways of oxidative stress induction. The finding will have ramifications in the understanding of disease pathogenesis, such as cardiovascular, cancer, inflammation, pathogenesis and ageing, where the antioxidant response is critical. For confidential support call the Samaritans on 08457 90 90 90 or visit a local Samaritans branch, see www.samaritans.org for details. In the U.S. call the National Suicide Prevention Line on 1-800-273-8255 or visit http://www.suicidepreventionlifeline.org/.